Class: Hormonal therapy
Generic Name: Abiraterone
Trade Name: Zytiga™
How is this drug used? Zytiga is used in combination with prednisone for metastatic, castration-resistant prostate cancer that has previously been treated with the chemotherapy drug Taxotere® (docetaxel).
What is the mechanism of action? Zytiga blocks the production of androgens (male hormones such as testosterone) not only by the testes but also by the adrenal glands and the tumor itself.
How is Zytiga given (administered)? Zytiga is a tablet that is taken orally (by mouth). Zytiga is taken on an empty stomach.
How are patients monitored? Patients will usually have scheduled meetings with their healthcare provider while they are being treated with Zytiga. Typically, blood will be drawn to check for side effects and to monitor functions of some organ systems. Patients may also undergo physical examinations or other measures to assess side effects and response to therapy.
What are the most common side effects of treatment with Zytiga?
What are some of the potentially serious side effects of Zytiga?
This is not a complete list of side effects. Some patients may experience other side effects that are not listed here. Patients may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.
Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.
What can patients do to help alleviate or prevent discomfort and side effects?
Are there any special precautions patients should be aware of before starting treatment?
When should patients notify their physician?
Tell your doctor if you experience any side effects that bother you or don’t go away. Some symptoms of potentially serious side effects include dizziness, fast heartbeats, feeling faint or lightheaded, headache, confusion, muscle weakness, pain in your legs, and swelling in your legs or feet.
What is a package insert?
A package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumers. A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug. By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. If you do not have the package insert for the drug you are using, your pharmacist or physician may be able to provide you with a copy.
Copyright © 2011 CancerConnect Last updated 05/11.
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Tags: A, Drug Dictionary, Hormonal Therapy