A gene which, when damaged or mutated, puts the carrier at a much higher risk for developing breast cancer and/or ovarian cancer than the general population. In a woman with a BRCA2 mutation, the estimated lifetime risk of developing breast cancer is 50-60%. BRCA1 and BRCA2 together account for about 80% of the breast cancer that occurs in women with strong family histories of the disease. BRCA is thought also to raise the risk for breast cancer in men. A genetic test for BRCA2 is available but is only recommended for women or men with strong family histories of breast or ovarian cancer. The ACS recommends that any women considering the test receive genetic counseling.