Tadalafil - TheGIConnection

Class: Other

Generic Name: Tadalafil

Trade Names: Cialis®

How is this drug used? Cialis is used to treat erectile dysfunction (ED) and/or the signs and symptoms of benign prostatic hyperplasia (BPH).

What is the mechanism of action? Cialis treats (but does not cure) ED by increasing blood flow to the penis; this helps a man to get an erection. In order for an erection to occur with Cialis, some form of sexual stimulation is necessary.

How is Cialis given (administered)? Cialis is taken orally (by mouth).

How are patients monitored? Patients will need to evaluated by their physician before starting treatment with Cialis. A thorough medical examination is necessary in order to diagnose erectile dysfunction or benign prostatic hyperplasia. An examination is also necessary in order to determine whether a man is healthy enough for sexual activity and whether he can safely take Cialis. Sexual activity may not be advisable for men with heart problems.

What are the most common side effects of treatment with Cialis?

Headache
Indigestion
Back pain
Muscle aches
Flushing
Stuffy or runny nose

What are some of the uncommon side effects of treatment with Cialis?

Changes in color vision
Sudden decrease or loss of vision in one or both eyes
An erection that lasts several hours (get immediate medical help if an erection lasts longer than four hours)
Sudden loss or decrease in hearing

This is not a complete list of side effects. Some patients may experience other side effects that are not listed here. Patients may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.

Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.

What can patients do to help alleviate or prevent discomfort and side effects?

Pay careful attention to the physician’s instructions, and discuss side effects with your physician.
Do not take Cialis if you take any drugs that contain nitrates. The combination of Cialis and nitrates can cause a life-threatening drop in blood pressure. Nitrates are present in some prescription drugs as well as recreational drugs known as “poppers.”
Do not drink too much alcohol when taking Cialis.

Are there any special precautions patients should be aware of before starting treatment?

Patients should inform their physician about all medical conditions, including current or past heart problems, stroke, high or low blood pressure, severe vision loss, retinitis pigmentosa, kidney problems, liver problems, blood cell problems, allergies, a deformed penis, Peyronie’s disease, an erection that lasted more than four hours, stomach ulcers, or bleeding problems.
Patients should inform their physician of any other medication or supplement they are taking (whether prescription or over-the-counter), including medicines that contain nitrates, alpha-blockers, other medicines to treat high blood pressure, protease inhibitors, oral antifungal drugs, antibiotics, or other treatments for ED.
Cialis does not protect against sexually transmitted diseases.
Cialis should not be used with other medical treatments for erectile dysfunction.
Cialis contains the same active ingredient as another drug called Adcirca. Adcirca is used for the treatment of pulmonary arterial hypertension. Cialis should not be used with Adcirca.

When should patients notify their physician?

Tell your doctor if you experience any side effects that bother you or don’t go away. Also seek immediate medical care if have an erection that lasts for longer than four hours (an erection that lasts for too long can permanently damage the penis); if you have chest pain, dizziness, or nausea during sex; if you experience a sudden loss or decrease of vision or hearing; or if you notice signs of an allergic reaction such as rash, hives, swelling of the lips, tongue, or throat, or difficulty breathing or swallowing.

What is a package insert? 

A package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumers. A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug. By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. If you do not have the package insert for the drug you are using, your pharmacist or physician may be able to provide you with a copy.

Important Limitations of Use

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