The treatment of hematological malignancies has different segments. Induction therapy refers to the methods used to destroy visible malignant cells in the blood and marrow to cause or "induce" a remission, which results in return of normal blood cells. Consolidation therapy is additional treatment given after remission is induced. Often, high doses of drugs are used in several short periods after treatment. The goal is to further decrease the concentration of residual malignant cells. The greater the reduction in malignant cells, the higher the probability that natural defenses will suppress the disease and result in a long-term remission. Maintenance or continuation therapy refers to the administration of drugs periodically for a long period of time (months or years) usually in lower doses that consolidation therapy.